News from the Dailey Lab

Recent News:

Lizzy Kruse receives Lowden Prize for Outreach and Engagement in Biology (May 2020)

Congratulations to Lizzy, one of two recipients of the Lowden Prize for Outreach and Engagement in Biology. This scholarship is awarded through the College of Liberal Arts and Sciences and recognizes a Biology, Biomedical Sciences, or Neuroscience student who has been highly engaged with the Department of Biology's outreach and recruiting events/activities. See the announcement here

Hussein Herz receives Master's of Science degree (Dec. 2019)

Hussein completed his MS in the iBio Program.  Congratulations Hussein!

Lizzy Kruse receives 2019 Iowa Neuroscience Institute (INI) Summer Scholar Award (May 2019)

Lizzy received a summer scholar award from the Iowa Neuroscience Institute to study effects of microglial depletion in mouse models of neuropathology.  See the announcement here. Congratulations Lizzy!

Dailey Lab receives DSHB Collaborative Award (Fall 2018)

The Dailey Lab received a pilot award from the Developmental Studies Hybridoma Bank at the University of Iowa for the project: New Antibody Tools for Exploring Transcriptional Regulation of Neuroimmune Cell Development and Function in Mouse Brain.  See the announcement here

Anya Kim received a Fulbright Research Award to conduct research in Spain (May 2018)

Anya will study microglia in the context of neurodegenerative diseases, including amyotrophic lateral sclerosis (ALS).  See the announcement here.  Congratulations Anya!

Lizzy Kruse receives ICRU Summer Fellowship (May 2018)

Lizzy received a summer research fellowship from the Iowa Center for Research by Undergraduates (ICRU) to study the functional roles of microglial cells in mouse models of neuropathology.  Congratulations Lizzy!

New pilot grant from the UI Center for Hypertension (July 2017)

The one-year pilot grant, “Nanoscale Therapeutics to Reduce Microglial-mediated CNS Inflammation Associated with Hypertension Sensitization,” supports a collaborative project between the Dailey lab (Biology), the lab of Dr. Alan Kim Johnson (Psychological & Brain Sciences), and the lab of Dr. Aliasger Salem (Laboratory of Advanced Drug and Gene Delivery, UI College of Pharmacy).  The goal is to design, synthesize, and characterize improved dendrimer-based nanocarriers to reduce microglial activation and proinflam­matory cytokine production, and to determine the extent to which anti-inflammatory nanoparticles abrogate sensitization of the hypertensive response in a rodent model.

Robert Taylor, Jr. receives Masters of Science degree (June 2017)

Congratulations to Robert for completing his Masters of Science degree in the iBio Program!  Robert is moving on to a research position in the Department of Psychiatry, Carver College of Medicine.

Anj Droe receives ICRU Summer Fellowship (May 2017)

Anj received a summer research fellowship from the Iowa Center for Research by Undergraduates (ICRU) to study the efficacy of nanoparticles to reduce neuroinflammatory responses in brain microglia.  Congratulations Anj!

Anya Kim receives an Excellence in Undergraduate Research Award (April 2017)

Ms. Kim was one of five recipients of the award presented by ICRU Director, Dr. Bob Kirby, at the University of Iowa Discovery & Innovation Awards Ceremony held at the Coralville Marriott Hotel on April 24, 2017.  Congratulations Anya!

Anya Kim receives 1st Place Symposium Presentation at regional neuroscience meeting in Ohio!

Ms. Kim was selected to present a platform talk at the 8th Annual Midwest Great Lakes Undergraduate Research Symposium (mGluRs), held Oct. 22 on the campus of Ohio State University.  The title of her talk was: "Exogenous Adenosine Protects BV-2 Microglia Cells in Simulated Ischemia."  In recognition of "research quality, originality, and significance to the field of Neuroscience," she was selected by vote of the attending faculty to receive the "1st Place Symposium Presentation."  Congratulations Anya!

Dailey lab awarded collaborative pilot grant to study links between pesticides, microglia, and autism

Recent studies have demonstrated links between pyrethroid pesticide exposure during fetal development and increased incidence of Autism Spectrum Disorders (ASDs).  However, the cellular and molecular mechanisms by which the pyrethroids impact the nervous system to increase risk of ASDs are unknown.  In a newly awarded pilot grant from the UI Environmental Health Sciences Research Center (EHSRC), we will test the hypothesis that pyrethroids and their metabolites alter the neuron environment yielding microglial activation and inflammatory events that increase risk for ASDs.  This is a collaborative project with Dr. Jonathan Doorn, Ph.D. (Associate Professor, Dept. of Pharmaceutical Sciences and Experimental Therapeutics, in the UI College of Pharmacy) and Dr. Hans-Joachim Lehmler, Ph.D. (Associate Professor, Dept. of Occupational and Environmental Health in the UI College of Public Health).  This research is funded by the National Institute for Environmental Health Sciences through the University of Iowa Environmental Health Sciences Research Center, NIEHS/NIH P30 ES005605.

 

Anya Kim receives American Heart Association summer research awardAmerican Heart Association Logo

Anya Kim has received an undergraduate student research program award from the Midwest Affiliate of the American Heart Association for her research project titled, “Adenosine Regulation of Microglial Survival and Function During Stroke.” The award will support her research on the project in the Dailey Lab.

 

Anya Kim selected for prestigious Fulbright Summer Institute ScholarshipAnya Kim Fulbright Summer Institute

Anya Kim has received a Fulbright Summer Institute scholarship to study at the University of Dundee and the University of Strathclyde in Scotland, on one of the most prestigious and selective summer scholarship programs operating world-wide.  Ms. Kim stated: "When I learned I had received a place in the Fulbright Summer Institutes, I was ecstatic. Getting the chance to experience another culture and live as a student in Scotland (one of my dream places to study abroad) will be a once in a lifetime opportunity. As an undergraduate researcher, I am also looking forward to meeting scientific researchers at these universities and getting to hear first-hand about their academic experiences and their current work. Lastly, I am so grateful for all the support I have received at the University of Iowa, and my advisors and mentors were invaluable as I worked on my application."  For more information on the program, see: http://www.fulbright.org.uk/news-events/news/announcing-the-fulbright-summer-institute-participants-2016

 

Shelley Lee receives 2016 Summer ICRU Fellowship.

Shelley LeeMs. Shelley Lee received a summer 2016 Iowa Center for Research by Undergraduates (ICRU) Fellowship to continue her research in the Dailey Lab.  Ms. Lee notes that: “The research project that I desire to work on is focused on how the different types of glial cells can affect neuronal damage after brain injury from exposure to toxins. What makes this research appealing to me is the entire experimentation process and the potential value of the results.”  Her project, entitled “Effects of Environmental Toxins on Brain Glial Cells,” will explore the effect of pesticides commonly used in homes and in agriculture on brain glial cell activation and survival.  This work is being done in collaboration with the lab of Dr. Jonathan Doorn (UI College of Pharmacy).  The collaborative project was funded by a pilot grant (“Contribution of Glial Cells to Neurotoxicity and Neurodegeneration,” J. Doorn, PI) from the Environmental Health Sciences Research Center (EHSRC), which is a National Institute of Environmental Health Sciences (NIEHS) Center of Excellence at the University of Iowa.

 

Robert Taylor receives 2016 Graduate College Summer FellowshipRobert Taylor

Robert Taylor, a Master’s Student in the iBio Program, received a fellowship from the Graduate College to support his work over the summer 2016 in the Dailey lab.  He is interested in the biology of a relatively understudied type of brain glial cell, called NG2/polydendrocytes.  His work will focus on understanding how these cells respond to brain injury, including stroke and alcohol exposure, in developing mice.

 

 

Congratulations!  Anya Kim receives a Clifford W. Hesseltine Award in Biology.

Dailey Lab member Anya Kim received a 2015-16 Clifford W. Hesseltine Award in Biology. This award is given annually to two Biology undergraduates in recognition of their excellence in formal coursework and in research undertaken within the Department of Biology.

 

Anya Kim – Latham FellowAnya Kim Cartoon Neuroscience

Anya Kim presented her Latham Fellows project, “Cartoon Neuroscience,” at the Latham Science Engagement Initiative's Project Engage Showcase on April 30.  Supported by a Latham Fellowship, Anya produced a comic book entitled, “Brains! A close-up look at what is going on inside your head.”  For more information on Anya’s vision for Cartoon Neuroscience, see: http://latham.uiowa.edu/projects/cartoon-neuroscience

To learn more about the Latham Science Engagement Initiative and Fellowship Program, see: http://latham.uiowa.edu/

 

Jennifer Wu – ICRU Academic Year Fellowship

Jennifer WuJennifer received a 2015-16 academic year ICRU fellowship.  Using cultured BV2 cells, her research aims to determine the extent to which cellular stressors (including immune activation) trigger changes in mitochondrial content within microglial cells.  This work seeks to understand the underlying mechanisms of stress-induced immune cell activation.  Jen will continue her studies over the summer as she works toward an Honor’s thesis.